Daniel Harrison Spofford (1842-1924) was engaged in the shoe trade in Knoxville, Tennessee, and became interested in Christian Science after his wife, Addie, studied with Mary Baker Eddy in 1870. After moving to Lynn, Massachusetts, he studied with Eddy in 1875 and became an effective Christian Science practitioner. He was soon put in charge of selling Eddy's book, Science and Health. By 1877, Spofford and Eddy's relationship had become strained. In 1878, he became a pawn in an elaborate hoax in which Asa Gilbert Eddy and Edward Arens were falsely accused of conspiring to murder Spofford.

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